I was out of town from the 1st through the 10th, but before I left there didn't appear to be any problems. I myself, have had none. There was a thread here when Panther was first released and everything seemed to be going well.
You can do a clean install (entirely erase your hardrive) or simply just do the easy upgrade. I'm really loving Panther as I have upgraded from 10.1.5 so it is a big leap for me.
BTW, there is already an update. 10.3.1 is available.